Building Prevention

We quantify the spine in routine computed tomography.
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OUR STORY

Bonescreen offers a novel, AI-based technology for non-invasive extraction of biomarkers from existing medical images to assist radiologists and clinicians in evaluating bone health.

products

SpineQ assists
clinicians in diagnosing*

Bonescreen SpineQ assists clinicians in diagnosing osteoporosis from almost any existing routine CT containing the spine. SpineQ provides a comprehensive spine report, including a level-wise annotation, a calibrated, reproducible bone mineral density measurement and osteoporotic fracture identification. It is designed to shorten reporting times and improve report quality by highlighting abnormal findings relevant for osteoporosis that are frequently overlooked.
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products

SpineR facilitates
your spine
processing*

SpineR is easily integrated in as the backbone of spine processing. In CT scans, SpineR segments and labels all vertebrae, identifies subregions and special points of interest. This is commonly needed in automated surgery planning, PACS-overlays, finite element modelling, 3D printing and more. SpineR outperforms current state of the art methods for spine segmentation in a computationally efficient way. Bonescreen readily identifies transitional vertebrae and all enumeration anomalies.
Request a demo

Products

SpineQ assists clinicians in diagnosing*

Bonescreen spineQ assists clinicians in diagnosing osteoporosis from almost any existing routine CT containing the spine. spineQ provides a comprehensive spine report, including a level-wise annotation, a calibrated, reproducible bone mineral density measurement and osteoporotic fracture identification. It is designed to shorten reporting times and improve report quality by highlighting abnormal findings relevant for osteoporosis that are frequently overlooked.

Request a demo

SpineR facilitates your spine processing*

Bonescreen spineR is easily integrated in many environments as the backbone of spine processing. In CT scans, SpineR segments and labels all vertebrae, identifies subregions and special points of interest, like commonly needed in automated surgery planning, PACS-overlays, finite element modelling, 3D printing and more. Bonescreen spineR outperforms current state of the art methods for spine segmentation in a computationally efficient way without the need for a GPU. Bonescreen readily identifies transitional vertebrae and all enumeration anomalies.

Request a demo

users

Bonescreen fits your needs

Optimised for your working environment

Research
Enabling bone researchers with advanced tools for precise segmentation and landmark detection, accelerating your research efforts.
PACS
Seamlessly integrating context information and anatomical guidance, enhancing the efficiency and completeness of patient records.
Surgeons
Intraoperative provision of level specific quantitative information on bone quality to surgeons in real time.
Clinicians
Providing clinicians with a quick, at-a-glance way to identify patients 
at risk, enhancing patient care and decision-making.
Radiologists
Empowering radiologists with precise, quantitative insights into bone diseases, such as osteoporosis, for more informed diagnoses.

Radiologists

Empowering radiologists with precise, quantitative insights into bone diseases, such as osteoporosis, for more informed diagnoses.

PACS

Seamlessly integrating context information and anatomical guidance, enhancing the efficiency and completeness of patient records.

Research

Enabling bone researchers with advanced tools for precise segmentation and landmark detection, accelerating their research efforts.

Clinicians

Providing clinicians with a quick, at-a-glance way to identify patients
at risk, enhancing patient care and decision-making.

Surgeons

Intraoperative provision of level specific quantitative information on bone quality to surgeons in real time.

about us

Bonescreen was founded in 2022 and is headquartered in Munich.

Bonescreen consists of a team rich in experience and diverse in background, be it physics, computer science, medicine, radiology, medical technology or business and finance

Collectively, we have 25 years of experience in radiology and 15 of experience in software engineering and machine learning.
Anjany Sekuboyina is an electrical engineer turned software engineer turned computer scientist. Expert at making machines understand medical images. Now a diplomat ensuring our doctors and developers speak the same language.
Anjany
CEO
Malek El Husseini is a biomedical professional with a background in software development and deep learning for medical
imaging. Malek ensures that our product meets customer,
regulatory, and quality
requirements.
Malek
CTO
Giles Tetteh is a biomedical engineer with special interest and experience in deep learning He ensures the smooth running of Bonescreen's I.T. infrastructure and puts together the bolts and nuts of the products.
Giles
CPO
Sebastian Rühling is a medical doctor specializing in neuroradiology. He is passionate about continuously improving data-driven healthcare technologies to deliver outcomes that really matter to patients.
Sebastian
CMO
Dominik Maurer splits his time between funding and business development. Prior to joining as CFO, he worked for J.P. Morgan in Sweden and the UK. If you want to get him excited outside of work, ask him about his Italian wine collection.
Dominik
CFO
Jan Kirschke is professor for
neuroradiology at TUM. He is an expert in osteoporosis and computational imaging and ensures our technology
meets patients needs.

Jan
Clinical Strategy Lead
Anjany Sekuboyina is an electrical engineer turned software engineer turned computer scientist. Expert at making machines understand medical images. Now a diplomat ensuring our doctors and developers speak the same language!
Anjany
CEO
Malek el Husseini is a biomedical professional with a background in software development and deep learning for medical imaging. Malek ensures that our product meets customer, regulatory, and quality requirements.
Malek
CTO
Giles Tetteh is a biomedical engineer with a special interest and experience in deep learning he ensures the smooth running of Bonescreen's i. T. Infrastructure and puts together the bolts and nuts of the products.
Giles
COO
Sebastian Rühling is a medical doctor specializing in neuroradiology. He is passionate about continuously improving data-driven healthcare technologies to deliver outcomes that really matter to patients.
Sebastian
CMO
Dominik Maurer splits his time between funding and business development. Prior to joining as CFO, he worked for J.P. Morgan in Sweden and the UK. If you want to get him excited outside of work, ask him about his Italian wine collection.
Dominik
CFO
Jan Kirschke is a professor of neuroradiology at Tum. He is an expert in osteoporosis and computational imaging and ensures our technology meets patient's needs.
Jan
Clinical Strategy Lead

Why do we need
biomarker extraction?

The doubling of the population older than 60 years during the next three decades will bring an explosion of bone-health-related conditions. Among these, Osteoporosis represents the most common bone disease in humans.

EFFECTIVE SCREENING

Osteoporosis is a disease that can be treated effectively, if diagnosed early. However, effective screening programs are currently missing. This is what Bonescreen aims to improve with our AI-based opportunistic screening software.

EARLY DIAGNOSIS

In a similar way, we are working on a solution to detect malignant bone lesions much earlier and more accurate compared to the current standard. All these patients may highly benefit from an earlier and more accurate diagnosis.

Preventive healthcare remains an underserved market

On average, European countries invest circa 3-4% of their total healthcare spend in preventive measures. The remaining 97% of costs goes to treating diseases.

REDUCED COST

This is too low, claims the OECD. Estimates imply that healthcare costs could be reduced by 30% if more preventive action were taken. In light of the €55bn the EU spends every year on the treatment of osteoporotic fractures, this implies cost savings of €15bn.

PREVERTION

Let alone the prevented loss of quality in life of the more than 4 million European patients who suffer an osteoporotic fracture each year. At Bonescreen, we build prevention. An impact tool to provide millions of Europeans access to preventive measures.

Our Aim

is to prevent fractures and make dignified ageing possible: Bonescreen will increase screening rates for osteoporosis by utilizing existing medical imaging data. With this, Bonescreen contributes to a prevention-based healthcare system away from primarily treating complications [Löffler MT et al., Eur Radiol. 2021; Sollmann N et al., J Bone Miner Res. 2022].

33%

of women and 20% of men older than 50 years will have an osteoporotic fracture during their lifetime. In Europe, osteoporotic fractures are the fourth leading cause of morbidity, after ischemic heart disease, dementia and lung cancer, however before chronic obstructive pulmonary disease and ischemic stroke.

91%

of patients who should be treated according to current osteoporosis guidelines do NOT receive their appropriate treatment in Germany, with almost similar numbers for whole Europe. This huge treatment gap is mainly caused by a diagnostic gap, which in turn is due to a lack of appropriate screening strategies [McCloskey E et al., Osteoporos Int 2021].

€55bn+

were spent in Europe to treat osteoporosis-related fragility fractures in 2019. Only €1.7bn were spent on medication that can prevent subsequent fractures. These numbers don’t account for additional personal and societal costs due to pain, reduced mobility, disability, lost working days and increased mortality [Kanis A et al., Arch Osteoporos. 2021].

81%

specificity was observed for opportunistic quantitative CT to predict vertebral fractures during follow-up in a study by Löffler et al.. The overall diagnostic performance, measured as “area under the curve” significantly outperformed dual x-ray absorptiometry in multiple studies [Chalhoub D et al., Bone 2016;Löffler MT et al., Eur Radiol. 2019].

97%

despite widely available and effective treatment options, more than 97% of osteoporosis-related health care costs are spent on treating fractures and only less than 3% on prevention. As osteoporosis is well treatable in early stages, many medical societies advocate a population-based screening program based on bone density measurements.

12%

of humans have anomalies at the spine, where additional lumbar vertebrae are the most frequent ones among Europeans, while thoracolumbar transitional vertebrae dominate in Asia. Our fully automated labelling and segmentation readily and reliably identifies those anomalies and is consistent with functional nerve anatomy [Ishiguro K et al. Sci Rep 2020].

Try today*

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*SpineQ is currently for research only and not available as a CE-marked or FDA-cleared clinical product. Spine R is not developed as a medical device software.

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